There are some things
a LUBRICAN’T™ do.

Ask your doctor
what plant-derived
ESTRACE® CREAM
CAN do.

More on ESTRACE®

Why ESTRACE®?

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

  • Plant-derived estrogen
    • There is no evidence that using a cream that contains "natural" estrogen is more effective than using the same dose of a cream that contains synthetic estrogen
  • Made with an emollient, which may prevent moisture loss
  • Maintenance therapy may not require monthly refills
    • Talk to your healthcare provider every 3 to 6 months about using the lowest dose possible, and whether or not you still need treatment with ESTRACE®
  • Dosing can be customized for you
    • The maintenance dose of ESTRACE® is about the size of a soybean

Ask your doctor if ESTRACE®
is right for you

More

ESTRACE® may help restore tissue.

ESTRACE® treats moderate to severe vaginal symptoms such as dryness, itching, and burning due to menopause.

dryness
itching
burning

These symptoms are often caused by vulvar and vaginal atrophy (VVA). VVA is a condition caused by the loss of estrogen due to menopause—a tissue issue. VVA may not get better without proper treatment. While lubricants may help with the symptoms of mild VVA, they can't treat the underlying cause.

Learn more about vulvar
and vaginal atrophy

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ESTRACE® has resources just for you.

ESTRACE® provides lots of resources to support you:

Find helpful resources

Indications and Usage

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

Important Risk Information
What is the most important information I should know about ESTRACE vaginal cream (an estrogen hormone)?
  • Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
  • Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer and blood clots. Using estrogens with progestins may increase your risk of dementia. You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

ESTRACE vaginal cream should not be used if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast tenderness, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, vaginal burning, irritation and itching.

Please see full Prescribing Information, which includes the Patient Information and Boxed Warning.

More
Indications and Usage

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

Important Risk Information
What is the most important information I should know about ESTRACE vaginal cream (an estrogen hormone)?
  • Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
  • Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer and blood clots. Using estrogens with progestins may increase your risk of dementia. You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

ESTRACE vaginal cream should not be used if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast tenderness, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, vaginal burning, irritation and itching.

Please see full Prescribing Information, which includes the Patient Information and Boxed Warning.