Savings Card

Join
THE VINE℠

Conversation
Starter Guide

Lubricants do not treat the underlying cause of vulvar and vaginal atrophy (VVA)

VVA is a postmenopausal condition caused by estrogen loss that results in the deterioration of vaginal tissue. While lubricants may help with symptoms of mild VVA, they can't treat its underlying cause.

Lubricants may not be enough when Tissue is the Issue.

ESTRACE® can help treat the underlying cause of VVA by replacing lost estrogen. Using only a lubricant to treat moderate to severe VVA can result in possible long-term vulvar and vaginal tissue damage. Ask your doctor if ESTRACE® is right for you.

More

ESTRACE® is a vaginal estrogen cream that treats moderate to severe vulvar and vaginal atrophy (VVA) symptoms:

dryness
itching
burning

Why a cream?

The ESTRACE® vaginal estrogen cream formula treats both inside the vagina and the vulva on the outside.

Why ESTRACE®?

  • Plant-derived estrogen
    • There is no evidence that using a cream that contains "natural" estrogen is more effective than using the same dose of a cream that contains synthetic estrogen
  • Made with an emollient, which may prevent moisture loss
  • Maintenance therapy may not require monthly refills
    • Talk to your healthcare provider every 3 to 6 months about using the lowest dose possible, and whether or not you still need treatment with ESTRACE®
  • Dosing can be customized for you
    • The maintenance dose of ESTRACE® is about the size of a soybean

More

ESTRACE® contains estrogen that is exclusively plant derived.

ESTRACE® is uniquely formulated for the symptoms of vulvar and vaginal atrophy (VVA).

  • In fact, the estrogen hormones found in ESTRACE® are chemically similar to the estrogen hormones your body made before menopause
    • There is no evidence that using a cream that contains "natural" estrogen is more effective than using the same dose of a cream that contains synthetic estrogen

More

Local vaginal estrogen treatment may help:

  • Normalize vaginal pH
  • Thicken tissue
  • Increase lubrication

Experiencing a tissue issue?

Speak with your doctor about your symptoms and whether local vaginal estrogen therapy may be right for you.

Important Risk Information
What is the most important information I should know about ESTRACE vaginal cream (an estrogen hormone)?
  • Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
  • Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer and blood clots. Using estrogens with progestins may increase your risk of dementia. You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

ESTRACE vaginal cream should not be used if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast tenderness, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, vaginal burning, irritation and itching.

Indications and Usage

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

Please see full Prescribing Information, which includes the Patient Information and Boxed Warning.

More
Indications and Usage

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

Important Risk Information
What is the most important information I should know about ESTRACE vaginal cream (an estrogen hormone)?
  • Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
  • Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer and blood clots. Using estrogens with progestins may increase your risk of dementia. You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

ESTRACE vaginal cream should not be used if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast tenderness, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, vaginal burning, irritation and itching.

Indications and Usage

ESTRACE® vaginal cream is a prescription medicine used to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause.

Please see full Prescribing Information, which includes the Patient Information and Boxed Warning.