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Vulvar and vaginal atrophy (VVA) may not get better without proper treatment

Vulvar and vaginal atrophy is a chronic condition commonly associated with the loss of estrogen due to menopause. Symptoms, which occur in and around the vagina, include:

dryness
itching
burning

VVA is progressive. As it moves from mild to moderate to severe, vaginal tissue can become less able to produce lubrication, inflamed, and irritated and itchy.

If you are experiencing VVA symptoms, you're not alone; VVA affects millions of women in the U.S.

A survey showed that:

  • Nearly 45% of all postmenopausal women suffer from VVA*
  • 63% did not know vaginal atrophy is a chronic condition*

Like many women, you may not know whether you have a tissue issue and rely on a lubricant to treat vaginal symptoms.

*Based on an international survey of 3520 postmenopausal women aged 55-65.

VVA may not get better without proper treatment. However, the moderate to severe symptoms of VVA can be treated with vaginal estrogen therapy.

If you have any of the symptoms described below, be sure to speak to your doctor.

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Here’s a quick and easy way to tell if you might have moderate to severe VVA.

Take a moment and check the symptoms that best apply to you.

  • I feel dry when I'm not being intimate, and the dryness has gotten worse
  • I am itchy
  • I experience burning

If you have one or more of these symptoms, print your Conversation Starter Guide. It can help you discuss your symptoms with your healthcare provider.

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More than a lubricant may be needed when Tissue is the Issue.

When used as prescribed, vaginal estrogen therapy is a recommended treatment for moderate to severe vulvar and vaginal atrophy.

Over-the-counter lubricants and moisturizers can provide only temporary relief of mild VVA symptoms. If you have moderate to severe symptoms or if your symptoms don't improve with the use of non-hormonal treatment, an FDA-approved vaginal estrogen cream like ESTRACE® may be an option to discuss with your doctor.

ESTRACE® may restore tissue, treating both the symptoms and underlying cause of VVA.

Vaginal health is an important part of your overall health, so talk to your doctor about the changes brought on by menopause.

Ask your doctor what ESTRACE® vaginal estrogen cream CAN do.

INDICATIONS AND USAGE

ESTRACE CREAM (estradiol vaginal cream, USP 0.01%) is a prescription medicine used to treat moderate to severe menopausal changes in and around the vagina.

IMPORTANT RISK INFORMATION
WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT ESTRACE VAGINAL CREAM (AN ESTROGEN HORMONE)?

Using estrogen alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using ESTRACE. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens alone or with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

Using estrogens alone or with progestins may increase your chances of getting heart attacks, strokes, breast cancer, blood clots, and dementia.

You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

Do not start using ESTRACE if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Tell your healthcare provider: if you are breastfeeding; about all of your medical problems, your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, fluid retention, vaginal yeast infection, vaginal burning, irritation and itching.

Please see full Prescribing Information, including Boxed Warning and Patient Information.

More
INDICATIONS AND USAGE

ESTRACE CREAM (estradiol vaginal cream, USP 0.01%) is a prescription medicine used to treat moderate to severe menopausal changes in and around the vagina.

IMPORTANT RISK INFORMATION
WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT ESTRACE VAGINAL CREAM (AN ESTROGEN HORMONE)?

Using estrogen alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using ESTRACE. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens alone or with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

Using estrogens alone or with progestins may increase your chances of getting heart attacks, strokes, breast cancer, blood clots, and dementia.

You and your healthcare provider should talk regularly about whether you still need treatment with ESTRACE vaginal cream.

Do not start using ESTRACE if you: have unusual vaginal bleeding, have or had certain cancers (including cancer of the breast or uterus), had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of the ingredients in ESTRACE vaginal cream, or think you may be pregnant.

Tell your healthcare provider: if you are breastfeeding; about all of your medical problems, your healthcare provider may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), migraine, endometriosis (including in women who have had a hysterectomy), lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

ESTRACE vaginal cream should be used at the lowest dose possible for your treatment only as long as needed. Although ESTRACE vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.

The most common side effects include: headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps and/or bloating, nausea and vomiting, hair loss, fluid retention, vaginal yeast infection, vaginal burning, irritation and itching.

Please see full Prescribing Information, including Boxed Warning and Patient Information.